The Graduate School

Helpful Information for Faculty and Staff Involved With National Institutes of Health (NIH) Training Grants

T32 General Info
Preparing T32 Applications
T32 Site Visit Tips
T32 Postaward Issues
UW-Madison T32 Database

Human Subjects/Vertebrate Animals/Biological Materials Protocols

Human Subjects:

NIH Application and UW-Madison Transmittal Form Instructions

It is important to read the instructions on preparing Institutional NRSA applications in the PHS 398 packet.  A description of their requirements for human subjects information is included in the specific instructions for the face page.  If appropriate, you may provide a list of IRB approvals from the individual trainers.  The assurance number for the University of Wisconsin-Madison is listed on the Office of Research and Sponsored Programs Frequently Requested Data for Applications page. On the face page of the application, you should provide this number and refer to the list of individual approvals in the space which requests the IRB approval date.

Human subject protocol numbers are listed in the EAST database developed by the Graduate School. While the database is not open to campus, access is currently being piloted with the T32 administrators. To request access to this database, contact Chip Quade at the Graduate School. The database will provide you with the PI, protocol number and approval date. Using this information, create a table of protocol information to include in the training plan as indicated in the instructions.  On the t-form, you should check "Yes" for the use of human subjects or human tissue. Instead of circling "pending" or "attached" under approval, write in that the use of human subjects will be reviewed through individual trainer protocols.

In addition to the t-form, you need to attach the Human Subjects Training Verification Letter. On the letter you should list all faculty and students participating in human subjects research. Faculty and students listed on the letter must complete the UW Human Subjects Training Module. In addition, the PI on the training grant must complete the UW Human Subjects Training Module.

Vertebrate Animals:
Read the instructions on preparing Institutional NRSA applications in the PHS 398 packet.  A description of their requirements for vertebrate animals information is included in the specific instructions for the face page.  If appropriate, you may provide a list of IACUC approvals from the individual trainers.  The assurance number for the University of Wisconsin-Madison is listed on the Office of Research and Sponsored Programs Frequently Requested Data for Applications page.  On the face page of the application, you may provide this number, but refer to the list of individual approvals in the space which requests the IACUC approval date.

Ask your faculty trainers whether they use vertebrate animals in their research.  For those who do, request protocol title, agency and grant number with which it is associated, review date, and approval number. Create table of all protocol information to include in the training plan as indicated in the instructions.  On the t-form, you should check "Yes" for the use of vertebrate animals, and add a note explaining that approvals associated with individual faculty projects are used.
 

Biological Materials:
If any of the projects involve the use of toxic, infectious or carcinogenic/mutagenic material of proven or potential hazard to humans, other animals or plants, or use recombinant DNA, you must check "Yes" in answer to this question on the transmittal form.  It is not necessary to collect information on protocol approvals from all of the involved faculty.  Instead, you may request an umbrella protocol approval from the UW's Office of Biological Safety (OBS) by completing the first page of the Biological Materials and Recombinant DNA Protocol form available on the OBS web site.  Both the protocol title and the grant title should be the title of your training grant proposal (add a note that it is a training grant if this is not obvious in the title).  Indicate on the form that the Biological safety review is covered by the individual trainers on their research grants.  The biological safety office will issue an approval form that you can attach to the t-form.  The information is not submitted to the NIH.